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Commentary
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Synergistic Signals in the Environment Steven F. Arnold and John A. McLachlan Tulane-Xavier Center for Bioenvironmental Research, Environmental Endocrinology Project, New Orleans, LA 70112 USA Abstract
Numerous endogenous signals (such as hormones and growth factors) or environmental signals (including chemicals or temperature) contribute to determining the overall biological response produced by cells. Some combinations of endogenous or environmental signals produce synergistic activity. This commentary examines the different types of interactions between signals that contribute to synergy at the biological level. Key words: environmental estrogens, hormones, synergy, temperature, turtles. Environ Health Perspect 104:1020-1023 (1996) Address correspondence to J.A. McLachlan, Tulane-Xavier Center for Bioenvironmental Research, 1430 Tulane Ave. SL3, New Orleans, LA 70112 USA. Received 25 July 1996 ; accepted 20 August 1996.
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